[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"nav-categories":3,"article-japanese-breakthrough-crispr-removes-extra-chromosome-in-down-syndrome-reshaping-cellular-norms":70},{"data":4},[5,37,57,64],{"name":6,"slug":7,"categories":8},"Productivity","productivity",[9,13,17,21,25,29,33],{"id":10,"title":11,"slug":12},17,"Branding","branding",{"id":14,"title":15,"slug":16},19,"Marketing","marketing",{"id":18,"title":19,"slug":20},20,"Work","work",{"id":22,"title":23,"slug":24},34,"Community","community",{"id":26,"title":27,"slug":28},21,"For newbies","for-newbies",{"id":30,"title":31,"slug":32},24,"Investment","investment",{"id":34,"title":35,"slug":36},22,"Finance","finance",{"name":38,"slug":39,"categories":40},"Tech","tech",[41,45,49,53],{"id":42,"title":43,"slug":44},28,"Technology","technology",{"id":46,"title":47,"slug":48},32,"Artificial Intelligence","artificial-intelligence",{"id":50,"title":51,"slug":52},26,"Security and protection","security-and-protection",{"id":54,"title":55,"slug":56},31,"YouTube Blog","youtube-blog",{"name":58,"slug":59,"categories":60},"News","news",[61],{"id":62,"title":58,"slug":63},18,"quasanews",{"name":65,"slug":66,"categories":67},"Business","business",[68],{"id":69,"title":65,"slug":66},16,{"post":71,"published_news":94,"popular_news":153,"categories":218},{"title":72,"description":73,"meta_title":72,"meta_description":74,"meta_keywords":75,"text":76,"slug":77,"created_at":78,"publish_at":78,"formatted_created_at":79,"category_id":42,"links":80,"view_type":83,"video_url":84,"views":85,"likes":86,"lang":87,"comments_count":86,"category":88},"Japanese Breakthrough: CRISPR Removes Extra Chromosome in Down Syndrome, Reshaping Cellular Norms","A groundbreaking development from Japan has sparked hope and debate in the medical world. Scientists have successfully used CRISPR technology—a precision DNA-editing tool — to remove the extra chromosome responsible for Down syndrome, marking a potential turning point in treating this genetic condition. In lab tests, the edited cells exhibited gene activity mirroring that of typical human cells, with heightened nervous system function and a normalized metabolic slowdown, suggesting the body could realign toward a “normal” state. While still in refinement and far from human trials, this advancement challenges the status quo of managing Down syndrome and raises both promise and ethical questions.","This breakthrough challenges the narrative that Down syndrome’s effects are immutable, offering a glimpse of genetic intervention at the chromosomal level.","As research progresses, this Japanese innovation could redefine Down syndrome treatment, but only time and scrutiny will reveal its true potential.","\u003Cp>A groundbreaking development from Japan has sparked hope and debate in the medical world. Scientists have successfully used CRISPR technology — a precision DNA-editing tool — to remove the extra chromosome responsible for Down syndrome, marking a potential turning point in treating this genetic condition.\u003C/p>\n\n\u003Cp>In lab tests, the edited cells exhibited gene activity mirroring that of typical human cells, with heightened nervous system function and a normalized metabolic slowdown, suggesting the body could realign toward a “normal” state. While still in refinement and far from human trials, this advancement challenges the status quo of managing Down syndrome and raises both promise and ethical questions.\u003C/p>\n\n\u003Chr />\n\u003Ch4>\u003Cstrong>CRISPR as a Surgical Scalpel\u003C/strong>\u003C/h4>\n\n\u003Cp>\u003Cimg alt=\"\" class=\"image-align-left\" height=\"299\" src=\"https://quasa.io/storage/photos/01/photo_2025-07-26_10-58-45.jpg\" width=\"300\" />CRISPR works like a molecular scalpel, targeting and excising specific DNA sequences with remarkable accuracy. In this case, Japanese researchers employed it to snip away the third copy of chromosome 21, known as trisomy 21, which causes Down syndrome.\u003C/p>\n\n\u003Cp>This condition, affecting about 1 in 700 births, stems from this genetic surplus, leading to developmental delays, physical traits, and health issues.\u003C/p>\n\n\u003Cp>The team’s approach leverages CRISPR’s ability to identify and delete the extra chromosome while preserving the two healthy copies, a feat that sidesteps the broader, less precise gene-editing methods of the past. Yet, the establishment’s enthusiasm for such precision should be tempered—early data suggests off-target cuts remain a risk, necessitating further refinement.\u003C/p>\n\n\u003Ch4>\u003Cstrong>Cells Realign to Typical Patterns\u003C/strong>\u003C/h4>\n\n\u003Cp>Post-editing, lab-grown cells showed striking changes. Genes associated with nervous system development ramped up, aligning with healthier brain function, while metabolic genes dialed back, reducing the overactivity linked to trisomy 21. This rebalancing hints at a cellular “reset,” with faster growth rates and reduced reactive oxygen species—markers of improved fitness and less biological stress.\u003C/p>\n\n\u003Cp>The results suggest that removing the extra chromosome could mitigate some Down syndrome effects at a fundamental level, a departure from current supportive therapies that only manage symptoms. However, these findings are confined to controlled environments, leaving doubts about how they’d translate to a living organism’s complexity.\u003C/p>\n\n\u003Chr />\n\u003Ch4>\u003Cstrong>Refinement and the Road to Human Trials\u003C/strong>\u003C/h4>\n\n\u003Cp>\u003Cimg alt=\"\" class=\"image-align-right\" height=\"225\" src=\"https://quasa.io/storage/photos/01/image - 2025-07-26T110940.780.jpg\" width=\"300\" />The technique is currently in a refinement phase, with researchers addressing safety concerns like unintended chromosomal damage. The next hurdle is human trials, a leap that demands rigorous testing to ensure efficacy and minimize risks. The establishment might hail this as a cure-in-the-making, but critical minds should note the gap between lab success and clinical reality — factors like delivery to all body cells, especially non-dividing ones like neurons, remain unproven.\u003C/p>\n\n\u003Cp>Ethical debates also loom large: should Down syndrome be “corrected,” or does this risk devaluing lives already enriched by the condition?\u003C/p>\n\n\u003Cp>\u003Cstrong>Also read:\u003C/strong>\u003C/p>\n\n\u003Cul>\n\t\u003Cli>\u003Ca href=\"https://quasa.io/media/elon-musk-s-ai-avatars-anya-and-rudi-hit-the-brakes-as-hedra-unveils-real-time-breakthrough\">Elon Musk’s AI Avatars Anya and Rudi Hit the Brakes, as Hedra Unveils Real-Time Breakthrough\u003C/a>\u003C/li>\n\t\u003Cli>\u003Ca href=\"https://quasa.io/media/japanese-scientists-develop-universal-artificial-blood-compatible-with-all-blood-types\">Japanese Scientists Develop Universal Artificial Blood Compatible with All Blood Types\u003C/a>\u003C/li>\n\t\u003Cli>\u003Ca href=\"https://quasa.io/media/japanese-scientists-develop-vr-game-that-could-improve-eyesight\">Japanese Scientists Develop VR Game That Could Improve Eyesight\u003C/a>\u003C/li>\n\t\u003Cli>\u003Ca href=\"https://quasa.io/media/earning-opportunities-in-cryptocurrency-for-cypriots-and-relocants-in-cyprus-via-quasa-connect\">Earning Opportunities in Cryptocurrency for Cypriots and Relocants in Cyprus via Quasa Connect\u003C/a>\u003C/li>\n\u003C/ul>\n\n\u003Chr />\n\u003Ch4>\u003Cstrong>A Balanced Perspective\u003C/strong>\u003C/h4>\n\n\u003Cp>This breakthrough challenges the narrative that Down syndrome’s effects are immutable, offering a glimpse of genetic intervention at the chromosomal level. Yet, the hype around CRISPR often outpaces its practical limits, and this case is no exception. The technique’s promise hinges on overcoming technical barriers and navigating the moral landscape — will it empower families or fuel eugenics fears? For now, it’s a proof of concept, not a solution, with human trials years away. As research progresses, this Japanese innovation could redefine Down syndrome treatment, but only time and scrutiny will reveal its true potential.\u003C/p>","japanese-breakthrough-crispr-removes-extra-chromosome-in-down-syndrome-reshaping-cellular-norms","2025-07-26T09:11:11.000000Z","26.07.2025",{"image":81,"thumb":82},"https://quasa.io/storage/images/news/oGocE3VR4pS2Bp0Sp7x76OTLkZK9D6UTDl79qg94.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/oGocE3VR4pS2Bp0Sp7x76OTLkZK9D6UTDl79qg94.jpg","small",null,2175,0,"en",{"id":42,"title":43,"slug":44,"meta_title":89,"meta_description":90,"meta_keywords":91,"deleted_at":84,"created_at":92,"updated_at":93,"lang":87},"Quasa media blog about growth hacking in Tech","All the most interesting and useful about technologies. Exclusive articles from technologies you won't find anywhere else.","Technology, tech, business, ai, gadget, gadgets, life hacks","2023-03-23T08:15:32.000000Z","2024-08-25T15:37:57.000000Z",[95,108,119,130,142],{"title":96,"description":97,"slug":98,"created_at":99,"publish_at":100,"formatted_created_at":101,"category":102,"links":103,"view_type":83,"video_url":84,"views":106,"likes":86,"lang":87,"comments_count":86,"is_pinned":107},"This AI Will Tell You Exactly How Attractive You Are — And It Only Takes 25 Seconds","There’s a new viral AI tool that does something most of us secretly want to know but are afraid to ask: it looks at your face and gives you a straight-up attractiveness score.","this-ai-will-tell-you-exactly-how-attractive-you-are-and-it-only-takes-25-seconds","2026-03-27T20:13:20.000000Z","2026-04-10T09:34:00.000000Z","10.04.2026",{"title":27,"slug":28},{"image":104,"thumb":105},"https://quasa.io/storage/images/news/eTdAX16TIQnnM1X90hkB2oOPixcWqRw3eZlaGUta.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/eTdAX16TIQnnM1X90hkB2oOPixcWqRw3eZlaGUta.jpg",138,false,{"title":109,"description":110,"slug":111,"created_at":112,"publish_at":113,"formatted_created_at":101,"category":114,"links":115,"view_type":83,"video_url":84,"views":118,"likes":86,"lang":87,"comments_count":86,"is_pinned":107},"Nubia Unveils RedMagic 11 Pro: The World’s First Gaming Smartphone with Liquid Cooling","The new flagship features a ceramic micropump, a massive 8,000mAh battery, and a Snapdragon 8 Elite Gen 5 processor.","nubia-unveils-redmagic-11-pro-the-world-s-first-gaming-smartphone-with-liquid-cooling","2026-03-26T06:45:27.000000Z","2026-04-10T06:40:00.000000Z",{"title":43,"slug":44},{"image":116,"thumb":117},"https://quasa.io/storage/images/news/g3jNseMCCzEO2cZreMfoeEH3R0kh2VsnDf511jwh.png","https://api.quasa.io/thumbs/news-thumb/images/news/g3jNseMCCzEO2cZreMfoeEH3R0kh2VsnDf511jwh.png",185,{"title":120,"description":121,"slug":122,"created_at":123,"publish_at":124,"formatted_created_at":101,"category":125,"links":126,"view_type":83,"video_url":84,"views":129,"likes":86,"lang":87,"comments_count":86,"is_pinned":107},"Chinese Startup Hypershell Unveils X Ultra Exoskeleton — More Powerful Than an E-Bike","Hypershell, a Chinese company specializing in wearable robotics, has just launched one of the most impressive consumer exoskeletons to date: the Hypershell X Ultra.","chinese-startup-hypershell-unveils-x-ultra-exoskeleton-more-powerful-than-an-e-bike","2026-03-25T21:36:46.000000Z","2026-04-10T03:27:00.000000Z",{"title":43,"slug":44},{"image":127,"thumb":128},"https://quasa.io/storage/images/news/xgiykS2Xj3WKWW2BoMKNqCWFJgIrJ1rfykipZMXy.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/xgiykS2Xj3WKWW2BoMKNqCWFJgIrJ1rfykipZMXy.jpg",294,{"title":131,"description":132,"slug":133,"created_at":134,"publish_at":135,"formatted_created_at":136,"category":137,"links":138,"view_type":83,"video_url":84,"views":141,"likes":86,"lang":87,"comments_count":86,"is_pinned":107},"Your Computer Mouse Can Now Eavesdrop on You","Researchers from the University of California, Irvine have demonstrated a surprising new security threat: an ordinary optical computer mouse can be turned into a covert microphone capable of listening to your conversations.","your-computer-mouse-can-now-eavesdrop-on-you","2026-03-25T21:21:22.000000Z","2026-04-09T11:13:00.000000Z","09.04.2026",{"title":43,"slug":44},{"image":139,"thumb":140},"https://quasa.io/storage/images/news/zvGSPNFVpmuJgnlniEHiwPc4aaeGYIVAuwxhouXu.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/zvGSPNFVpmuJgnlniEHiwPc4aaeGYIVAuwxhouXu.jpg",856,{"title":143,"description":144,"slug":145,"created_at":146,"publish_at":147,"formatted_created_at":136,"category":148,"links":149,"view_type":83,"video_url":84,"views":152,"likes":86,"lang":87,"comments_count":86,"is_pinned":107},"Figure AI Founder Brett Adcock Launches Hark: A New Lab Building True Personal AGI","Brett Adcock, the founder of humanoid robotics company Figure AI, has quietly launched his next ambitious venture: Hark, an AI laboratory dedicated to creating the world’s most advanced personal intelligence.","figure-ai-founder-brett-adcock-launches-hark-a-new-lab-building-true-personal-agi","2026-03-25T20:23:25.000000Z","2026-04-09T09:11:00.000000Z",{"title":43,"slug":44},{"image":150,"thumb":151},"https://quasa.io/storage/images/news/C1UuYbaKmb90FPNMq9HupZ84jzRUQmO6HBbSPEPh.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/C1UuYbaKmb90FPNMq9HupZ84jzRUQmO6HBbSPEPh.jpg",974,[154,167,181,193,206],{"title":155,"description":156,"slug":157,"created_at":158,"publish_at":159,"formatted_created_at":160,"category":161,"links":162,"view_type":83,"video_url":84,"views":165,"likes":166,"lang":87,"comments_count":86,"is_pinned":107},"The Anatomy of an Entrepreneur","Entrepreneur is a French word that means an enterpriser. Enterprisers are people who undertake a business or enterprise with the chance of earning profits or suffering from loss.","the-anatomy-of-an-entrepreneur","2021-08-04T15:18:21.000000Z","2025-12-14T06:09:00.000000Z","14.12.2025",{"title":65,"slug":66},{"image":163,"thumb":164},"https://quasa.io/storage/images/news/mVsXPTMuHZuI7UXCsENgL1Qwp1uSOf7Rz3uVPMfm.webp","https://api.quasa.io/thumbs/news-thumb/images/news/mVsXPTMuHZuI7UXCsENgL1Qwp1uSOf7Rz3uVPMfm.webp",68775,2,{"title":168,"description":169,"slug":170,"created_at":171,"publish_at":172,"formatted_created_at":173,"category":174,"links":175,"view_type":178,"video_url":84,"views":179,"likes":180,"lang":87,"comments_count":86,"is_pinned":107},"Advertising on QUASA","QUASA MEDIA is read by more than 400 thousand people a month. We offer to place your article, add a link or order the writing of an article for publication.","advertising-on-quasa","2022-07-06T07:33:02.000000Z","2025-12-15T17:33:02.000000Z","15.12.2025",{"title":58,"slug":63},{"image":176,"thumb":177},"https://quasa.io/storage/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.jpg","large",68335,4,{"title":182,"description":183,"slug":184,"created_at":185,"publish_at":186,"formatted_created_at":187,"category":188,"links":189,"view_type":83,"video_url":84,"views":192,"likes":180,"lang":87,"comments_count":86,"is_pinned":107},"What is a Startup?","A startup is not a new company, not a tech company, nor a new tech company. You can be a new tech company, if your goal is not to grow high and fast; then, you are not a startup. ","what-is-a-startup","2021-08-04T12:05:17.000000Z","2025-12-17T13:02:00.000000Z","17.12.2025",{"title":65,"slug":66},{"image":190,"thumb":191},"https://quasa.io/storage/images/news/EOsQhSW3VXyG7a6NPdE1oZd00xfJXe3bjY5aJGb7.webp","https://api.quasa.io/thumbs/news-thumb/images/news/EOsQhSW3VXyG7a6NPdE1oZd00xfJXe3bjY5aJGb7.webp",66362,{"title":194,"description":195,"slug":196,"created_at":197,"publish_at":198,"formatted_created_at":199,"category":200,"links":201,"view_type":83,"video_url":84,"views":204,"likes":166,"lang":87,"comments_count":205,"is_pinned":107},"Top 5 Tips to Make More Money as a Content Creator","Content creators are one of the most desired job titles right now. Who wouldn’t want to earn a living online?","top-5-tips-to-make-more-money-as-a-content-creator","2022-01-17T17:31:51.000000Z","2026-01-17T11:30:00.000000Z","17.01.2026",{"title":19,"slug":20},{"image":202,"thumb":203},"https://quasa.io/storage/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.jpg",40634,1,{"title":207,"description":208,"slug":209,"created_at":210,"publish_at":211,"formatted_created_at":212,"category":213,"links":214,"view_type":178,"video_url":84,"views":217,"likes":166,"lang":87,"comments_count":86,"is_pinned":107},"8 Logo Design Tips for Small Businesses","Your logo tells the story of your business and the values you stand for.","8-logo-design-tips-for-small-businesses","2021-12-04T21:59:52.000000Z","2025-05-05T03:30:00.000000Z","05.05.2025",{"title":15,"slug":16},{"image":215,"thumb":216},"https://quasa.io/storage/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.jpg","https://api.quasa.io/thumbs/news-thumb/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.jpg",39940,[219,220,221,222,223,224,225,226,227,228,229,230,231],{"title":23,"slug":24},{"title":47,"slug":48},{"title":55,"slug":56},{"title":43,"slug":44},{"title":51,"slug":52},{"title":31,"slug":32},{"title":35,"slug":36},{"title":27,"slug":28},{"title":19,"slug":20},{"title":15,"slug":16},{"title":58,"slug":63},{"title":11,"slug":12},{"title":65,"slug":66}]