[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"nav-categories":3,"article-fat-cells-have-a-memory-of-obesity-study-finds":70},{"data":4},[5,37,57,64],{"name":6,"slug":7,"categories":8},"Productivity","productivity",[9,13,17,21,25,29,33],{"id":10,"title":11,"slug":12},17,"Branding","branding",{"id":14,"title":15,"slug":16},19,"Marketing","marketing",{"id":18,"title":19,"slug":20},20,"Work","work",{"id":22,"title":23,"slug":24},34,"Community","community",{"id":26,"title":27,"slug":28},21,"For newbies","for-newbies",{"id":30,"title":31,"slug":32},24,"Investment","investment",{"id":34,"title":35,"slug":36},22,"Finance","finance",{"name":38,"slug":39,"categories":40},"Tech","tech",[41,45,49,53],{"id":42,"title":43,"slug":44},28,"Technology","technology",{"id":46,"title":47,"slug":48},32,"Artificial Intelligence","artificial-intelligence",{"id":50,"title":51,"slug":52},26,"Security and protection","security-and-protection",{"id":54,"title":55,"slug":56},31,"YouTube Blog","youtube-blog",{"name":58,"slug":59,"categories":60},"News","news",[61],{"id":62,"title":58,"slug":63},18,"quasanews",{"name":65,"slug":66,"categories":67},"Business","business",[68],{"id":69,"title":65,"slug":66},16,{"post":71,"published_news":95,"popular_news":164,"categories":235},{"title":72,"description":73,"meta_title":72,"meta_description":73,"meta_keywords":74,"text":75,"slug":76,"created_at":77,"publish_at":78,"formatted_created_at":79,"category_id":22,"links":80,"view_type":84,"video_url":82,"views":85,"likes":86,"lang":87,"comments_count":88,"category":89},"Fat cells have a 'memory' of obesity, study finds","Most people who lose weight through dieting will see it creep back up, leading to a cycle of \"yo-yo dieting\" that's hard on the body.","yo-yo dieting fat cells keep a memory original body mass","\u003Cp>Hello!\u003C/p>\n\n\u003Cp>Most people who lose weight through dieting will see it creep back up, leading to a cycle of "yo-yo dieting" that's hard on the body. A new study suggests fat cells keep a memory of previous weight gain, which may help to explain why this happens.\u003C/p>\n\n\u003Cp>\u003Cpicture class=\"image-align-left\">\u003Csource srcset=\"https://cdn.quasa.io/photos/photo/29_11/fat3.webp\" type=\"image/webp\">\u003Cimg alt=\"Fat cells have a 'memory' of obesity, study finds\" class=\"image-align-left\" height=\"169\" src=\"https://cdn.quasa.io/photos/photo/29_11/fat3.jpg\" width=\"300\" />\u003C/picture>Losing weight can be a lot of work, which makes it all the more frustrating when, little by little, the weight creeps back. Now, a study suggests that fat cells retain a memory or past obesity, which may prime the cells to grow when exposed to high-fat foods.\u003C/p>\n\n\u003Cp>The research "might add to the growing body of evidence that disproves lack of willpower as the underlying force behind 'weight cycling,'" said Dr. Katherine H. Saunders, an obesity physician at Weill Cornell Medicine and co-founder of FlyteHealth, a software and clinical services company for medical obesity treatment, who was not involved in the study.\u003C/p>\n\n\u003Cp>Without weight-loss medications or bariatric surgery, most people will return to their original body mass within a few years of losing weight through a diet. This can lead to "yo-yo dieting." Scientists don't know why this happens, but genetics, environment and health history likely all play a role. Now, a study published Nov. 18 in the journal Nature adds an essential piece to this puzzle. Chemical modifications on DNA, or epigenetic markers, may help the cells retain a memory of their past state.\u003C/p>\n\n\u003Cp>While DNA stays mostly the same throughout life, the way the body reads its DNA code is dynamic, thanks to epigenetic modifications: By tightly packing some sections of DNA and covering other parts of the molecule with chemical tags, these modifications change how a cell uses the DNA and, consequently, how the cell functions.\u003C/p>\n\n\u003Cp>\u003Cpicture class=\"image-align-left\">\u003Csource srcset=\"https://cdn.quasa.io/photos/photo/29_11/fat4.webp\" type=\"image/webp\">\u003Cimg alt=\"Fat cells have a 'memory' of obesity, study finds\" class=\"image-align-left\" height=\"203\" src=\"https://cdn.quasa.io/photos/photo/29_11/fat4.jpg\" width=\"300\" />\u003C/picture>In the new study, scientists observed mice that were given a high-fat diet before switching back to a normal diet to return them to their starting weight. Once they dropped the extra weight, the mice were metabolically indistinguishable from mice that were never fed a fatty diet. However, when the researchers looked at the mice’s fat cells, they found that despite their weight loss, the cells still carried epigenetic changes that had arisen during the weight gain.\u003C/p>\n\n\u003Cp>To check whether this also happens in humans, the team then analyzed cells from people who had undergone bariatric surgery. There, they found patterns of gene activity that suggested epigenetic changes took place and persisted after weight loss, said study co-author Laura Hinte, a doctoral student of nutrition and metabolic epigenetics at ETH Zurich.\u003C/p>\n\n\u003Cp>"Adipocytes [fat cells] are known to go through a kind of identity crisis in obesity — they kind of forget who they are and what they are supposed to be doing," Hinte told Quisa. This work showed those changes remained "long after the mice had lost weight," she said, and a similar identity shift might be happening in \u003Ca href=\"https://quasa.io/media/want-to-lose-your-weight-add-a-breakfast-of-oats-in-your-diet\">human fat cells\u003C/a>, the data suggest.\u003C/p>\n\n\u003Cp>Further evidence came from a closer look at the mice's fat cells. When removed from the formerly obese mice and bathed in glucose and palmitate — high-sugar and fatty ingredients — the fat cells enlarged more quickly than those taken from control mice. The formerly obese mice also gained weight more quickly when provided a high-calorie diet, compared with the controls.\u003C/p>\n\n\u003Cp>"The epigenetic changes didn't have consequences for the mice as long as they were in a healthy environment," Hinte said, referencing when the mice were given a standard diet.\u003C/p>\n\n\u003Cp>\u003Cpicture class=\"image-align-left\">\u003Csource srcset=\"https://cdn.quasa.io/photos/photo/29_11/fat2.webp\" type=\"image/webp\">\u003Cimg alt=\"Fat cells have a 'memory' of obesity, study finds\" class=\"image-align-left\" height=\"300\" src=\"https://cdn.quasa.io/photos/photo/29_11/fat2.jpg\" width=\"225\" />\u003C/picture>Other mechanisms are likely involved in weight rebound, Hinte added. For instance, it's "very likely" that this memory exists in other cell types in the body, such as neurons, where these modifications may affect appetite in people who have lost weight.\u003C/p>\n\n\u003Cp>The study doesn't prove that epigenetic changes directly cause \u003Ca href=\"https://quasa.io/media/16-best-ways-to-maintain-weight-loss\">weight rebound\u003C/a>. However, it strongly suggests that these mechanisms may play a role in the complex interplay of forces that drive obesity.\u003C/p>\n\n\u003Cp>Dr. Fatima Cody Stanford, an associate professor of medicine and pediatrics at Harvard Medical School, who was not involved in the study, said it "offers valuable insights into why maintaining \u003Ca href=\"https://quasa.io/media/scientists-discover-gene-that-causes-you-to-gain-more-weight-from-the-same-food\">weight \u003C/a>loss is challenging."\u003C/p>\n\n\u003Cp>She noted, however, that the observations in lab mice "may not fully represent the complexity of human obesity." Another major caveat to this study is whether it has practical applications, she said. To date, scientists haven't found many molecules that can tweak the epigenetics of DNA in a cell's nucleus.\u003C/p>\n\n\u003Cp>The work also "strengthens the argument for early intervention when it comes to both weight gain and weight regain," Saunders told Quasa.\u003C/p>\n\n\u003Cp>Thank you!\u003Cbr />\nJoin us on social networks!\u003Cbr />\nSee you!\u003C/p>","fat-cells-have-a-memory-of-obesity-study-finds","2024-11-29T16:45:18.000000Z","2024-11-30T11:00:00.000000Z","30.11.2024",{"image":81,"image_webp":82,"thumb":83,"thumb_webp":83},"https://cdn.quasa.io/images/news/nWKI9soSpZi8p1RwyAWcSD7THMbEM3yGzMjBOPHp.webp",null,"https://cdn.quasa.io/thumbs/news-thumb/images/news/nWKI9soSpZi8p1RwyAWcSD7THMbEM3yGzMjBOPHp.webp","small",1013,3,"en",0,{"id":22,"title":23,"slug":24,"meta_title":90,"meta_description":91,"meta_keywords":92,"deleted_at":82,"created_at":93,"updated_at":94,"lang":87},"Community Building: Grow Your Audience & Network | QUASA","From heart warming stories to everyday heroes and shocking events, we've got the latest real life stories to keep you entertained","All the community news from around the world","2025-01-10T08:48:23.000000Z","2026-04-22T15:32:26.000000Z",[96,111,124,137,150],{"title":97,"description":98,"slug":99,"created_at":100,"publish_at":101,"formatted_created_at":102,"category":103,"links":104,"view_type":84,"video_url":82,"views":109,"likes":88,"lang":87,"comments_count":88,"is_pinned":110},"Grok Voice Think Fast 1.0: The $3/Hour Voice AI That’s About to Replace Entire Call Centers","xAI just released Grok Voice Think Fast 1.0 — and the economics of voice AI have officially broken.","grok-voice-think-fast-1-0-the-3-hour-voice-ai-that-s-about-to-replace-entire-call-centers","2026-04-27T09:48:30.000000Z","2026-04-29T11:36:00.000000Z","29.04.2026",{"title":58,"slug":63},{"image":105,"image_webp":106,"thumb":107,"thumb_webp":108},"https://cdn.quasa.io/images/news/CaLws6TKSTHgTelvUiTRfEcaVyOIWzXu77AvSM8G.jpg","https://cdn.quasa.io/images/news/CaLws6TKSTHgTelvUiTRfEcaVyOIWzXu77AvSM8G.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/CaLws6TKSTHgTelvUiTRfEcaVyOIWzXu77AvSM8G.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/CaLws6TKSTHgTelvUiTRfEcaVyOIWzXu77AvSM8G.webp",76,false,{"title":112,"description":113,"slug":114,"created_at":115,"publish_at":116,"formatted_created_at":102,"category":117,"links":118,"view_type":84,"video_url":82,"views":123,"likes":88,"lang":87,"comments_count":88,"is_pinned":110},"DeepSeek-V4: The Open-Source Model That Just Made 1 Million Tokens Routine","DeepSeek has dropped the preview of DeepSeek-V4 — a direct, no-compromise open-source challenger to Claude, GPT-5, and Gemini.","deepseek-v4-the-open-source-model-that-just-made-1-million-tokens-routine","2026-04-27T09:31:03.000000Z","2026-04-29T09:20:00.000000Z",{"title":47,"slug":48},{"image":119,"image_webp":120,"thumb":121,"thumb_webp":122},"https://cdn.quasa.io/images/news/tbCZ87Xbns1do1OzsCcVqR7Hyb5TxUo0d57URt3Z.jpg","https://cdn.quasa.io/images/news/tbCZ87Xbns1do1OzsCcVqR7Hyb5TxUo0d57URt3Z.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/tbCZ87Xbns1do1OzsCcVqR7Hyb5TxUo0d57URt3Z.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/tbCZ87Xbns1do1OzsCcVqR7Hyb5TxUo0d57URt3Z.webp",91,{"title":125,"description":126,"slug":127,"created_at":128,"publish_at":129,"formatted_created_at":102,"category":130,"links":131,"view_type":84,"video_url":82,"views":136,"likes":88,"lang":87,"comments_count":88,"is_pinned":110},"OpenAI’s $10B DeployCo Play: Turning Private Equity Portfolios into an Enterprise AI Launchpad","OpenAI has just made its boldest move yet to crack the enterprise market. Instead of relying on traditional sales teams or pure software licensing, the company is betting big on implementation — and it’s doing so through a massive new joint venture called DeployCo.","openai-s-10b-deployco-play-turning-private-equity-portfolios-into-an-enterprise-ai-launchpad","2026-04-27T09:17:47.000000Z","2026-04-29T06:05:00.000000Z",{"title":43,"slug":44},{"image":132,"image_webp":133,"thumb":134,"thumb_webp":135},"https://cdn.quasa.io/images/news/FTRf04i8FQ4x4ILvUmSbpmzrD6LzgCZHmqpnMqUj.jpg","https://cdn.quasa.io/images/news/FTRf04i8FQ4x4ILvUmSbpmzrD6LzgCZHmqpnMqUj.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/FTRf04i8FQ4x4ILvUmSbpmzrD6LzgCZHmqpnMqUj.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/FTRf04i8FQ4x4ILvUmSbpmzrD6LzgCZHmqpnMqUj.webp",107,{"title":138,"description":139,"slug":140,"created_at":141,"publish_at":142,"formatted_created_at":102,"category":143,"links":144,"view_type":84,"video_url":82,"views":149,"likes":88,"lang":87,"comments_count":88,"is_pinned":110},"ComfyUI Cracks Open Real Human Faces in Seedance 2.0 — But Is It Really Fixed?","Anyone who has spent time wrestling with Seedance 2.0 in ComfyUI knows the pain. The model is incredibly powerful — cinematic camera control, native audio sync, buttery motion — but the built-in censorship made generating videos with actual human faces a nightmare.","comfyui-cracks-open-real-human-faces-in-seedance-2-0-but-is-it-really-fixed","2026-04-27T09:02:16.000000Z","2026-04-29T03:50:00.000000Z",{"title":27,"slug":28},{"image":145,"image_webp":146,"thumb":147,"thumb_webp":148},"https://cdn.quasa.io/images/news/isioWpVV24Sw2xRNu9cnOgRXYy28g1ASNCW254ZX.jpg","https://cdn.quasa.io/images/news/isioWpVV24Sw2xRNu9cnOgRXYy28g1ASNCW254ZX.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/isioWpVV24Sw2xRNu9cnOgRXYy28g1ASNCW254ZX.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/isioWpVV24Sw2xRNu9cnOgRXYy28g1ASNCW254ZX.webp",118,{"title":151,"description":152,"slug":153,"created_at":154,"publish_at":155,"formatted_created_at":156,"category":157,"links":158,"view_type":84,"video_url":82,"views":163,"likes":88,"lang":87,"comments_count":88,"is_pinned":110},"Sierra AI Just Reinvented the Software Engineering Interview — And It’s Brilliant","Sierra AI — the enterprise AI startup co-founded by Bret Taylor (OpenAI board chairman and former Co-CEO of Salesforce) — just published a quietly revolutionary blog post titled The AI-native interview.","sierra-ai-just-reinvented-the-software-engineering-interview-and-it-s-brilliant","2026-04-23T17:49:41.000000Z","2026-04-28T11:39:00.000000Z","28.04.2026",{"title":19,"slug":20},{"image":159,"image_webp":160,"thumb":161,"thumb_webp":162},"https://cdn.quasa.io/images/news/DJ894jC3gLB6PUzLn5skZgOEm7fBiFooBdGQUwpC.jpg","https://cdn.quasa.io/images/news/DJ894jC3gLB6PUzLn5skZgOEm7fBiFooBdGQUwpC.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/DJ894jC3gLB6PUzLn5skZgOEm7fBiFooBdGQUwpC.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/DJ894jC3gLB6PUzLn5skZgOEm7fBiFooBdGQUwpC.webp",205,[165,178,194,206,221],{"title":166,"description":167,"slug":168,"created_at":169,"publish_at":170,"formatted_created_at":171,"category":172,"links":173,"view_type":84,"video_url":82,"views":176,"likes":177,"lang":87,"comments_count":88,"is_pinned":110},"The Anatomy of an Entrepreneur","Entrepreneur is a French word that means an enterpriser. Enterprisers are people who undertake a business or enterprise with the chance of earning profits or suffering from loss.","the-anatomy-of-an-entrepreneur","2021-08-04T15:18:21.000000Z","2025-12-14T06:09:00.000000Z","14.12.2025",{"title":65,"slug":66},{"image":174,"image_webp":82,"thumb":175,"thumb_webp":175},"https://cdn.quasa.io/images/news/mVsXPTMuHZuI7UXCsENgL1Qwp1uSOf7Rz3uVPMfm.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/mVsXPTMuHZuI7UXCsENgL1Qwp1uSOf7Rz3uVPMfm.webp",72160,2,{"title":179,"description":180,"slug":181,"created_at":182,"publish_at":183,"formatted_created_at":184,"category":185,"links":186,"view_type":191,"video_url":82,"views":192,"likes":193,"lang":87,"comments_count":88,"is_pinned":110},"Advertising on QUASA","QUASA MEDIA is read by more than 400 thousand people a month. We offer to place your article, add a link or order the writing of an article for publication.","advertising-on-quasa","2022-07-06T07:33:02.000000Z","2025-12-15T17:33:02.000000Z","15.12.2025",{"title":58,"slug":63},{"image":187,"image_webp":188,"thumb":189,"thumb_webp":190},"https://cdn.quasa.io/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.jpg","https://cdn.quasa.io/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/45SvmdsTQbiyc3nxgbyHY1mpVbisYyub2BCHjqBL.webp","large",71942,4,{"title":195,"description":196,"slug":197,"created_at":198,"publish_at":199,"formatted_created_at":200,"category":201,"links":202,"view_type":84,"video_url":82,"views":205,"likes":193,"lang":87,"comments_count":88,"is_pinned":110},"What is a Startup?","A startup is not a new company, not a tech company, nor a new tech company. You can be a new tech company, if your goal is not to grow high and fast; then, you are not a startup. ","what-is-a-startup","2021-08-04T12:05:17.000000Z","2025-12-17T13:02:00.000000Z","17.12.2025",{"title":65,"slug":66},{"image":203,"image_webp":82,"thumb":204,"thumb_webp":204},"https://cdn.quasa.io/images/news/EOsQhSW3VXyG7a6NPdE1oZd00xfJXe3bjY5aJGb7.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/EOsQhSW3VXyG7a6NPdE1oZd00xfJXe3bjY5aJGb7.webp",69526,{"title":207,"description":208,"slug":209,"created_at":210,"publish_at":211,"formatted_created_at":212,"category":213,"links":214,"view_type":84,"video_url":82,"views":219,"likes":177,"lang":87,"comments_count":220,"is_pinned":110},"Top 5 Tips to Make More Money as a Content Creator","Content creators are one of the most desired job titles right now. Who wouldn’t want to earn a living online?","top-5-tips-to-make-more-money-as-a-content-creator","2022-01-17T17:31:51.000000Z","2026-01-17T11:30:00.000000Z","17.01.2026",{"title":19,"slug":20},{"image":215,"image_webp":216,"thumb":217,"thumb_webp":218},"https://cdn.quasa.io/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.jpg","https://cdn.quasa.io/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/gP8kiumBPpJmQv6SMieXiX1tDetx43VwFfO1P4Ca.webp",43416,1,{"title":222,"description":223,"slug":224,"created_at":225,"publish_at":226,"formatted_created_at":227,"category":228,"links":229,"view_type":191,"video_url":82,"views":234,"likes":177,"lang":87,"comments_count":88,"is_pinned":110},"8 Logo Design Tips for Small Businesses","Your logo tells the story of your business and the values you stand for.","8-logo-design-tips-for-small-businesses","2021-12-04T21:59:52.000000Z","2025-05-05T03:30:00.000000Z","05.05.2025",{"title":15,"slug":16},{"image":230,"image_webp":231,"thumb":232,"thumb_webp":233},"https://cdn.quasa.io/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.jpg","https://cdn.quasa.io/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.webp","https://cdn.quasa.io/thumbs/news-thumb/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.jpg","https://cdn.quasa.io/thumbs/news-thumb/images/news/Wbx2NtS1CnTupgoQbpFMGspJ5jm4uob2hDOq33r0.webp",42429,[236,237,238,239,240,241,242,243,244,245,246,247,248],{"title":23,"slug":24},{"title":47,"slug":48},{"title":55,"slug":56},{"title":43,"slug":44},{"title":51,"slug":52},{"title":31,"slug":32},{"title":35,"slug":36},{"title":27,"slug":28},{"title":19,"slug":20},{"title":15,"slug":16},{"title":58,"slug":63},{"title":11,"slug":12},{"title":65,"slug":66}]